Mission and goals

Member site

The OC3 is an international consortium of cohort studies whose mission is to address scientific aims important for understanding ovarian cancer risk, early detection, tumor heterogeneity, and prognosis. The OC3 is part of the NCI Cohort Consortium, which is an extramural-intramural partnership to address the need for large-scale collaborations and provides the super-structure (but not funding) for managing the OC3. The OC3 currently has 28 participating, on-going cohort studies and we expect there to be over 8,000 invasive ovarian cancer cases among more than 1.5 million women. The goals of the OC3 are to bring together cohorts with ovarian cancer endpoints for pooled projects, build a focused group of ovarian cancer researchers, and develop a comprehensive approach that integrates questionnaire and pathology data with biomarkers, genetics, and tissue.




Recent Publications

  1. Peres, L. C., Mallen, A. R., Townsend, M. K., Poole, E. M., Trabert, B., Allen, N. E., . . . Tworoger, S. S. (2019). High Levels of C-Reactive Protein Are Associated with an Increased Risk of Ovarian Cancer: Results from the Ovarian Cancer Cohort Consortium. Cancer Res, 79(20), 5442-5451. doi:10.1158/0008-5472.CAN-19-1554


  1. Trabert, B., Poole, E. M., White, E., Visvanathan, K., Adami, H. O., Anderson, G. L., . . . Ovarian Cancer Cohort, C. (2019). Analgesic Use and Ovarian Cancer Risk: An Analysis in the Ovarian Cancer Cohort Consortium. J Natl Cancer Inst, 111(2), 137-145. doi:10.1093/jnci/djy100


  1. Fortner, R. T., Poole, E. M., Wentzensen, N. A., Trabert, B., White, E., Arslan, A. A., . . . Tworoger, S. S. (2018). Ovarian cancer risk factors by tumor aggressiveness: an analysis from the Ovarian Cancer Cohort Consortium. Int J Cancer. doi:10.1002/ijc.32075

Ovarian Cancer Cohort Consortium